Sesquiterpenoids from the herb of Leonurus japonicus.

نویسندگان

  • Liang Xiong
  • Qin-Mei Zhou
  • Cheng Peng
  • Xiao-Fang Xie
  • Li Guo
  • Xiao-Hong Li
  • Juan Liu
  • Zhao-Hua Liu
  • Ou Dai
چکیده

Two new sesquiterpenoids, (-)-(1S*,2S*,3R*)-3-ethoxycupar-5-ene-1,2-diol (1) and (-)-(1S*,4S*,9S*)-1,9-epoxybisabola-2,10-diene-4-ol (2), along with six known compounds 3-8, were isolated from the EtOH extract of the herb of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. In the in vitro assays, compounds 7 and 8 showed obvious antibacterial activity against several bacteria strains, while compound 3 significantly inhibited abnormal increase of platelet aggregation induced by ADP.

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عنوان ژورنال:
  • Molecules

دوره 18 5  شماره 

صفحات  -

تاریخ انتشار 2013